Abstract
Dendritic cells (DCs) are unique antigen presenting cells, which upon maturation change from a specialized antigen-capturing cell towards a professional antigen presenting cells. In this study, a 2-D DIGE analysis of immature and mature DCs was performed, to identify proteins changing in expression upon maturation. The protein expression profile of immature and mature DCs, derived from CD14+ peripheral blood monocytes was investigated using two pH ranges (pH 4-7 and 6-9) (n = 4). Ninety one differentially expressed spots (p
Original language | English |
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Journal | Proteomics - Clinical Applications |
Volume | 2 |
Issue number | 9 |
Pages (from-to) | 1349-1360 |
ISSN | 1862-8346 |
DOIs | |
Publication status | Published - 2008 |