Protein engineering of enzymes for process applications

Research output: Contribution to journalJournal articleResearchpeer-review


Scientific progress in the field of enzyme modification today enables the opportunity to tune a given biocatalyst for a specific industrial application. Much work has been focused on extending the substrate repertoire and altering selectivity. Nevertheless, it is clear that many new forthcoming opportunities will be targeted on modification to enable process application. This article discusses the challenges involved in enzyme modification focused on process requirements, such as the need to fulfill reaction thermodynamics, specific activity under the required conditions, kinetics at required concentrations, and stability. Finally, future research directions are discussed, including the integration of biocatalysis with neighboring chemical steps.
Original languageEnglish
JournalCurrent Opinion in Chemical Biology
Issue number2
Pages (from-to)310-316
Publication statusPublished - 2013


Dive into the research topics of 'Protein engineering of enzymes for process applications'. Together they form a unique fingerprint.

Cite this