Proficiency of WHO Global Foodborne Infections Network External Quality Assurance System participants in the identification and susceptibility testing of thermo-tolerant Campylobacter spp. from 2003-2012

Susanne Karlsmose Pedersen*, Jaap A Wagenaar, Håkan Vigre, Louise Roer, Matthew Mikoleit, Awa Aidara-Kane, Amy L Cawthorne, Frank Møller Aarestrup, Rene S. Hendriksen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

204 Downloads (Pure)

Abstract

Campylobacter spp. are food- and water borne pathogens. While rather accurate estimates for these pathogens are available in industrialized countries, a lack of diagnostic capacity in developing countries limits accurate assessments of prevalence in many regions. Proficiency in the identification and susceptibility testing of these organisms is critical for surveillance and control efforts. The aim of the study was to assess performance for identification and susceptibility testing of thermo-tolerant Campylobacter among laboratories participating in the World Health Organization (WHO) Global Foodborne Infections Network (GFN) External Quality Assurance System (EQAS) over a nine year period.Participants (primarily national level laboratories) were encouraged to self-evaluate performance as part of continuous quality improvement.The ability to correctly identify Campylobacter spp. varied by year and ranged from 61.9 % (2008) to 90.7 % (2012), and the ability to correctly perform antimicrobial susceptibility testing (AST) for Campylobacter spp. appeared to steadily increase from 91.4 % to 93.6 % in the test period (2009-2012).Poorest performance (60.0 % correct identification and 86.8 % correct AST results) was observed in African laboratories.Overall, approximately 10 % of laboratories reported either an incorrect identification or antibiogramme. As most participants were (supra)-national reference laboratories, these data raise significant concerns regarding capacity and proficiency at the local, clinical level. Addressing these diagnostic challenges is critical for both patient level management and broader surveillance and control efforts.
Original languageEnglish
Article numbere01066-18
JournalJournal of Clinical Microbiology
Volume56
Issue number11
Number of pages9
ISSN0095-1137
DOIs
Publication statusPublished - 2018

Cite this

@article{48d6f506ad024935a37ee53149497f9b,
title = "Proficiency of WHO Global Foodborne Infections Network External Quality Assurance System participants in the identification and susceptibility testing of thermo-tolerant Campylobacter spp. from 2003-2012",
abstract = "Campylobacter spp. are food- and water borne pathogens. While rather accurate estimates for these pathogens are available in industrialized countries, a lack of diagnostic capacity in developing countries limits accurate assessments of prevalence in many regions. Proficiency in the identification and susceptibility testing of these organisms is critical for surveillance and control efforts. The aim of the study was to assess performance for identification and susceptibility testing of thermo-tolerant Campylobacter among laboratories participating in the World Health Organization (WHO) Global Foodborne Infections Network (GFN) External Quality Assurance System (EQAS) over a nine year period.Participants (primarily national level laboratories) were encouraged to self-evaluate performance as part of continuous quality improvement.The ability to correctly identify Campylobacter spp. varied by year and ranged from 61.9 {\%} (2008) to 90.7 {\%} (2012), and the ability to correctly perform antimicrobial susceptibility testing (AST) for Campylobacter spp. appeared to steadily increase from 91.4 {\%} to 93.6 {\%} in the test period (2009-2012).Poorest performance (60.0 {\%} correct identification and 86.8 {\%} correct AST results) was observed in African laboratories.Overall, approximately 10 {\%} of laboratories reported either an incorrect identification or antibiogramme. As most participants were (supra)-national reference laboratories, these data raise significant concerns regarding capacity and proficiency at the local, clinical level. Addressing these diagnostic challenges is critical for both patient level management and broader surveillance and control efforts.",
author = "{Karlsmose Pedersen}, Susanne and Wagenaar, {Jaap A} and H{\aa}kan Vigre and Louise Roer and Matthew Mikoleit and Awa Aidara-Kane and Cawthorne, {Amy L} and Aarestrup, {Frank M{\o}ller} and Hendriksen, {Rene S.}",
year = "2018",
doi = "10.1128/JCM.01066-18",
language = "English",
volume = "56",
journal = "Journal of Clinical Microbiology",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "11",

}

Proficiency of WHO Global Foodborne Infections Network External Quality Assurance System participants in the identification and susceptibility testing of thermo-tolerant Campylobacter spp. from 2003-2012. / Karlsmose Pedersen, Susanne; Wagenaar, Jaap A; Vigre, Håkan; Roer, Louise; Mikoleit, Matthew; Aidara-Kane, Awa; Cawthorne, Amy L; Aarestrup, Frank Møller; Hendriksen, Rene S.

In: Journal of Clinical Microbiology, Vol. 56, No. 11, e01066-18, 2018.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Proficiency of WHO Global Foodborne Infections Network External Quality Assurance System participants in the identification and susceptibility testing of thermo-tolerant Campylobacter spp. from 2003-2012

AU - Karlsmose Pedersen, Susanne

AU - Wagenaar, Jaap A

AU - Vigre, Håkan

AU - Roer, Louise

AU - Mikoleit, Matthew

AU - Aidara-Kane, Awa

AU - Cawthorne, Amy L

AU - Aarestrup, Frank Møller

AU - Hendriksen, Rene S.

PY - 2018

Y1 - 2018

N2 - Campylobacter spp. are food- and water borne pathogens. While rather accurate estimates for these pathogens are available in industrialized countries, a lack of diagnostic capacity in developing countries limits accurate assessments of prevalence in many regions. Proficiency in the identification and susceptibility testing of these organisms is critical for surveillance and control efforts. The aim of the study was to assess performance for identification and susceptibility testing of thermo-tolerant Campylobacter among laboratories participating in the World Health Organization (WHO) Global Foodborne Infections Network (GFN) External Quality Assurance System (EQAS) over a nine year period.Participants (primarily national level laboratories) were encouraged to self-evaluate performance as part of continuous quality improvement.The ability to correctly identify Campylobacter spp. varied by year and ranged from 61.9 % (2008) to 90.7 % (2012), and the ability to correctly perform antimicrobial susceptibility testing (AST) for Campylobacter spp. appeared to steadily increase from 91.4 % to 93.6 % in the test period (2009-2012).Poorest performance (60.0 % correct identification and 86.8 % correct AST results) was observed in African laboratories.Overall, approximately 10 % of laboratories reported either an incorrect identification or antibiogramme. As most participants were (supra)-national reference laboratories, these data raise significant concerns regarding capacity and proficiency at the local, clinical level. Addressing these diagnostic challenges is critical for both patient level management and broader surveillance and control efforts.

AB - Campylobacter spp. are food- and water borne pathogens. While rather accurate estimates for these pathogens are available in industrialized countries, a lack of diagnostic capacity in developing countries limits accurate assessments of prevalence in many regions. Proficiency in the identification and susceptibility testing of these organisms is critical for surveillance and control efforts. The aim of the study was to assess performance for identification and susceptibility testing of thermo-tolerant Campylobacter among laboratories participating in the World Health Organization (WHO) Global Foodborne Infections Network (GFN) External Quality Assurance System (EQAS) over a nine year period.Participants (primarily national level laboratories) were encouraged to self-evaluate performance as part of continuous quality improvement.The ability to correctly identify Campylobacter spp. varied by year and ranged from 61.9 % (2008) to 90.7 % (2012), and the ability to correctly perform antimicrobial susceptibility testing (AST) for Campylobacter spp. appeared to steadily increase from 91.4 % to 93.6 % in the test period (2009-2012).Poorest performance (60.0 % correct identification and 86.8 % correct AST results) was observed in African laboratories.Overall, approximately 10 % of laboratories reported either an incorrect identification or antibiogramme. As most participants were (supra)-national reference laboratories, these data raise significant concerns regarding capacity and proficiency at the local, clinical level. Addressing these diagnostic challenges is critical for both patient level management and broader surveillance and control efforts.

U2 - 10.1128/JCM.01066-18

DO - 10.1128/JCM.01066-18

M3 - Journal article

VL - 56

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 11

M1 - e01066-18

ER -