Production of n-glycoproteins for enzyme assisted glycomodification

Shamim Herbert Rahmann (Inventor), Carsten Behrens (Inventor), Malene Bech Vester-Christensen (Inventor), Henrik Clausen (Inventor), Yang Zhang (Inventor), Adnan Fevzi Halim (Inventor), Eric Bennett (Inventor)

Research output: Patent

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The present invention relates to a cell comprising a gene encoding a polypeptide of interest, wherein the polypeptide of interest is expressed comprisingone or more posttranslational modification patterns. These modifications are useful for example in improvement of pharmacokinetic properties, i.e. by attaching PEG chains to proteins. The present invention also relates to methods for producing the antibodies and compositions comprising the antibodies, and their uses.

Original languageEnglish
IPCC12N 15/ 90 A I
Patent numberWO2017008982
Filing date19/01/2017
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date16/07/2015
Priority numberUS201562193433P
Publication statusPublished - 19 Jan 2017


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