Processes for the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity.

Christian Bille Jendresen (Inventor), Solvej Siedler (Inventor), Steen Gustav Stahlhut (Inventor), Alex Toftgaard Nielsen (Inventor)

Research output: Patent

183 Downloads (Pure)

Abstract

The present invention generally relates to the field of biotechnology as it applies to the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity. More particularly, the present invention pertains to polypeptides having tyrosine ammonia lyase activity and high substrate specificity towards tyrosine, which makes them particularly suitable in the production of p-coumaric acid and other hydroxycinnamic acids. The present invention thus provides processes for the production of p-coumaric acid and other hydroxycinnamic acids employing these polypeptides as well as recombinant host cells expressing same.

Original languageEnglish
IPCC12N 9/ 88 A I
Patent numberWO2016008886
Filing date21/01/2016
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date14/07/2014
Priority numberEP20140176975
Publication statusPublished - 21 Jan 2016

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