Process Flow Sheet Generation & Design through a Group Contribution Approach

Loïc d'Anterroches

Research output: Book/ReportPh.D. thesisResearch

3670 Downloads (Pure)


This thesis describes the development of a framework for the synthesis and design of process flowsheets using a systematic strategy for computer aided flowsheet design (CAFD). The developed framework addresses the formulation, solution and analysis of CAFD problems, based on the concept of a process group, which represents a single unit operation or a set of unit operations in the same way an atom or a group of atoms represent a molecular group. Through the definition of the process groups, their connectivity rules and their contributions to specific flowsheet properties, chemical process flowsheets are synthesized, modelled and analysed in the same way as chemical molecules are synthesized and tested for their properties. To achieve this, simple and efficient methods for process synthesis and design have been developed. The synthesis of the chemical process flowsheet alternatives is performed through a reverse flowsheet property approach, where the process group building blocks are combined to form flowsheet structures having desired (target) properties. Then the design of the most promising flowsheet alternatives is performed through a reverse simulation approach, where the design of the unit operations is back calculated from the specifications of their inlet and outlet streams inherited from the corresponding process groups. The developed framework and associated computer aided methods and tools have been tested using a series of case studies and application examples.
Original languageEnglish
Place of PublicationKgs. Lyngby
PublisherTechnical University of Denmark
Number of pages208
ISBN (Print)87-91435-35-8
Publication statusPublished - Mar 2006


Integrated Process/Product Synthesis and Design Through a Reverse Modelling Approach

d'Anterroches, L., Gani, R., Villadsen, J., Kraslawski, A. & Pistikopoulos, S.



Project: PhD

Cite this

d'Anterroches, L. (2006). Process Flow Sheet Generation & Design through a Group Contribution Approach. Technical University of Denmark.