Process Design and Optimization of Biocatalytic Reactions

Juliet J. Victoria*, John Woodley*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

Abstract

Biocatalysis is a potentially sustainable alternative to traditional chemical catalysis to produce industrially relevant molecules. The flexibility offered by protein engineering (and immobilization) to enable the enzyme to be designed, engineered,
or evolved has expanded the catalytic capability enormously and given great impetus to the field. To date several 100 biocatalytic processes have been successfully translated at scale. However, the number is relatively small as compared to
chemical catalysis. Challenges related to the enzyme, process, and the market have impeded its implementation. This chapter aims to explain the crucial aspects related to biocatalytic process development and optimization to maximize the odds of successful implementation at scale.
Original languageEnglish
Title of host publicationChemistry, Molecular Sciences and Chemical Engineering
Number of pages20
PublisherElsevier
Publication date2022
ISBN (Electronic)9780124095472
DOIs
Publication statusPublished - 2022

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