Prevalence of Campylobacter concisus in diarrhoea of immunocompromised patients

Rune Aabenhus, Henrik Permin, Stephen L.W. On, Leif P. Andersen

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    The importance of Campylobacter species other than C. jejuni/coli in diarrhoeal disease is largely unknown. We wished to determine the prevalence and clinical presentation of C. concisus infection in patients with enteric disease in a tertiary hospital. Stool specimens were routinely tested for the presence of Campylobacter species, by use of the filter isolation method. The medical records of the C. concisus-positive patients were reviewed. Of 224 Campylobacter isolates obtained, 110 were identified as C. concisus. Concomitant infection occurred in only 27% of cases. 13 means of protein profiling we assigned C. concisus into 2 groups. The predominant C. concisus group 2 was the only strain to infect immunocompetent patients and children: 71% of the infected patients were immunocompromised, the majority being adults (84%). C. concisus may be a frequent cause of diarrhoea in immunocompromised patients. Two groups of C. concisus were found and these groups possible vary in their pathogenic potential.
    Original languageEnglish
    JournalScandinavian Journal of Infectious Diseases
    Volume34
    Issue number4
    Pages (from-to)248-252
    ISSN0036-5548
    DOIs
    Publication statusPublished - 2002

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