Prevalence of Antibodies Against Foot-and-Mouth Disease Virus in Cattle in Kasese and Bushenyi Districts in Uganda

F. N. Mwiine, C. Ayebazibwe, W. Olaho-Mukani, Søren Alexandersen, Kirsten Tjørnehøj

    Research output: Contribution to journalJournal articleResearchpeer-review

    263 Downloads (Pure)

    Abstract

    Abstract: The aim of this study was to determine the seroprevalence and serotype-specificity of the circulating antibodies against Foot-and-Mouth Disease Virus (FMDV) in cattle in K asese and Bushenyi districts in Uganda. A total of 309 serum samples were collected and tested for antibodies against Non-Structural (NS) and Structural Proteins (SP) using Ceditest® FMDV-NS and C editest® FMDV type O test kits. Seroprevalences were much higher in Kasese in both tests (61 and 43%, respectively) than in Bushenyi (3 and 4% , respectively). A high proportion of sera, that tested positive in the NSP test, were subjected to seven serotype specific blocking ELISAs for antibodies against the seven FMDV serotypes (O, A, C, Asia 1, SAT 1, SAT 2 and SAT 3). The study showed presence of antibodies against four FMDV serotypes with decreasing magnitude as follows: O> SAT 1> SAT 3/SAT 2. It is recommended to develop sampling schemes to include virus recovery and identification, as well as to focus serum sampling on young unvaccinated stock.
    Original languageEnglish
    JournalInternational Journal of Animal and Veterinary Advance
    Volume2
    Issue number3
    Pages (from-to)89-96
    ISSN2041-2908
    Publication statusPublished - 2010

    Keywords

    • Cattle
    • Antibody
    • Uganda
    • Foot-and-mouth disease,
    • ELISAs

    Fingerprint Dive into the research topics of 'Prevalence of Antibodies Against Foot-and-Mouth Disease Virus in Cattle in Kasese and Bushenyi Districts in Uganda'. Together they form a unique fingerprint.

    Cite this