Preparation of polystyrene-poly(ethylene glycol) diblock copolymer by "living" free radical polymerization

Xianyi Chen, Bo Gao, Jørgen Kops, Walther Batsberg

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Amphiphilic diblock copolymer containing segments of polystyrene and monomethoxypoly(ethylene glycol) (PS-b-PEG) was synthesised by a novel method. Initially, the adduct (BZ-TEMPO) obtained by reacting benzoyl peroxide, styrene, and 2,2,6,6-tetramethyl-piperidinyl-1-oxy (TEMPO) was isolated, characterised and hydrolysed. Conditions for the synthesis and hydrolysis of BZ-TEMPO were investigated and the hydrolysed product (HO-TEMPO) containing a primary hydroxyl group has been isolated in improved yield. The hydroxyl group of HO-TEMPO was coupled with tosylated PEG to yield the macroinitiator PEG terminated with a TEMPO unit (MPEG-TEMPO), which was further used to prepare the diblock copolymer PS-b-PEG by 'living' free radical polymerisation of styrene. The product was purified and identified by H-1 n.m.r. and GPC. However, large amounts of homopolystyrene was also formed by simultaneous thermal initiation and polymerisation. (C) 1997 Elsevier Science Ltd.
Original languageEnglish
JournalPolymer
Volume39
Issue number4
Pages (from-to)911-915
ISSN0032-3861
DOIs
Publication statusPublished - 1998

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