Abstract
A new method for C-C bond formation was developed based on in situ
cyanosilylation of cyclic Schiff bases using KCN, TMSCl, KI and
ZnI2. This method was used to prepare the potent
-glucosidase inhibitor
1,4-dideoxy-1,4-imino-D-arabinitol 14-C labelled at C-5.Keywords:
in situ cyanosilylation; 14-C labelled hydroxylated pyrrolidines;
glycosidase inhibitors.
Original language | English |
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Journal | J. Labelled Cpd. Radiopharm. |
Volume | 42 |
Pages (from-to) | 1145-1159 |
Publication status | Published - 1999 |