Preliminary investigation of an ultrasound method for estimating pressure changes in deep-positioned vessels.

Jacob Bjerring Olesen, Carlos Armando Villagómez Hoyos, Marie Sand Traberg, Adrian J. Y. Chee, Billy Y. S. Yiu, Chung Kit Ho, Alfred C. H. Yu, Jørgen Arendt Jensen

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This paper presents a method for measuring pressure changes in deep-tissue vessels using vector velocity ultrasound
data. The large penetration depth is ensured by acquiring data using a low frequency phased array
transducer. Vascular pressure changes are then calculated from 2-D angle-independent vector velocity fields using
a model based on the Navier-Stokes equations. Experimental scans are performed on a fabricated flow phantom
having a constriction of 36% at a depth of 100 mm. Scans are carried out using a phased array transducer
connected to the experimental scanner, SARUS. 2-D fields of angle-independent vector velocities are acquired
using directional synthetic aperture vector flow imaging. The obtained results are evaluated by comparison to a
3-D numerical simulation model with equivalent geometry as the designed phantom. The study showed pressure
drops across the constricted phantom varying from -40 Pa to 15 Pa with a standard deviation of 32%, and a
bias of 25% found relative to the peak simulated pressure drop. This preliminary study shows that pressure can
be estimated non-invasively to a depth that enables cardiac scans, and thereby, the possibility of detecting the
pressure drops across the mitral valve.
Original languageEnglish
Title of host publicationProceedings of SPIE
EditorsNeb Duric, Brecht Heyde
Number of pages6
PublisherSPIE - International Society for Optical Engineering
Publication date2016
Article number97900J
Publication statusPublished - 2016
EventSPIE Medical Imaging 2016 : Ultrasonic Imaging and Tomography - Town & Country Resort and Convention Cente, San Diego, United States
Duration: 27 Feb 20163 Mar 2016
Conference number: 9790


ConferenceSPIE Medical Imaging 2016
LocationTown & Country Resort and Convention Cente
CountryUnited States
CitySan Diego
Internet address


  • Medical ultrasound
  • Pressure estimation
  • Vector flow imaging
  • Synthetic aperture

Cite this

Olesen, J. B., Villagómez Hoyos, C. A., Traberg, M. S., Chee, A. J. Y., Yiu, B. Y. S., Ho, C. K., Yu, A. C. H., & Jensen, J. A. (2016). Preliminary investigation of an ultrasound method for estimating pressure changes in deep-positioned vessels. In N. Duric, & B. Heyde (Eds.), Proceedings of SPIE (Vol. 9790). [97900J] SPIE - International Society for Optical Engineering.