Abstract
This paper presents a method for measuring pressure changes in deep-tissue vessels using vector velocity ultrasound
data. The large penetration depth is ensured by acquiring data using a low frequency phased array
transducer. Vascular pressure changes are then calculated from 2-D angle-independent vector velocity fields using
a model based on the Navier-Stokes equations. Experimental scans are performed on a fabricated flow phantom
having a constriction of 36% at a depth of 100 mm. Scans are carried out using a phased array transducer
connected to the experimental scanner, SARUS. 2-D fields of angle-independent vector velocities are acquired
using directional synthetic aperture vector flow imaging. The obtained results are evaluated by comparison to a
3-D numerical simulation model with equivalent geometry as the designed phantom. The study showed pressure
drops across the constricted phantom varying from -40 Pa to 15 Pa with a standard deviation of 32%, and a
bias of 25% found relative to the peak simulated pressure drop. This preliminary study shows that pressure can
be estimated non-invasively to a depth that enables cardiac scans, and thereby, the possibility of detecting the
pressure drops across the mitral valve.
data. The large penetration depth is ensured by acquiring data using a low frequency phased array
transducer. Vascular pressure changes are then calculated from 2-D angle-independent vector velocity fields using
a model based on the Navier-Stokes equations. Experimental scans are performed on a fabricated flow phantom
having a constriction of 36% at a depth of 100 mm. Scans are carried out using a phased array transducer
connected to the experimental scanner, SARUS. 2-D fields of angle-independent vector velocities are acquired
using directional synthetic aperture vector flow imaging. The obtained results are evaluated by comparison to a
3-D numerical simulation model with equivalent geometry as the designed phantom. The study showed pressure
drops across the constricted phantom varying from -40 Pa to 15 Pa with a standard deviation of 32%, and a
bias of 25% found relative to the peak simulated pressure drop. This preliminary study shows that pressure can
be estimated non-invasively to a depth that enables cardiac scans, and thereby, the possibility of detecting the
pressure drops across the mitral valve.
Original language | English |
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Title of host publication | Proceedings of SPIE |
Editors | Neb Duric, Brecht Heyde |
Number of pages | 6 |
Volume | 9790 |
Publisher | SPIE - International Society for Optical Engineering |
Publication date | 2016 |
Article number | 97900J |
DOIs | |
Publication status | Published - 2016 |
Event | SPIE Medical Imaging 2016 - Town & Country Resort and Convention Cente, San Diego, United States Duration: 27 Feb 2016 → 3 Mar 2016 https://spie.org/conferences-and-exhibitions/past-conferences-and-exhibitions/medical-imaging-2016 |
Conference
Conference | SPIE Medical Imaging 2016 |
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Location | Town & Country Resort and Convention Cente |
Country/Territory | United States |
City | San Diego |
Period | 27/02/2016 → 03/03/2016 |
Internet address |
Keywords
- Medical ultrasound
- Pressure estimation
- Vector flow imaging
- Synthetic aperture