Preliminary investigation of an ultrasound method for estimating pressure changes in deep-positioned vessels.

Jacob Bjerring Olesen, Carlos Armando Villagómez Hoyos, Marie Sand Traberg, Adrian J. Y. Chee, Billy Y. S. Yiu, Chung Kit Ho, Alfred C. H. Yu, Jørgen Arendt Jensen

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    Abstract

    This paper presents a method for measuring pressure changes in deep-tissue vessels using vector velocity ultrasound
    data. The large penetration depth is ensured by acquiring data using a low frequency phased array
    transducer. Vascular pressure changes are then calculated from 2-D angle-independent vector velocity fields using
    a model based on the Navier-Stokes equations. Experimental scans are performed on a fabricated flow phantom
    having a constriction of 36% at a depth of 100 mm. Scans are carried out using a phased array transducer
    connected to the experimental scanner, SARUS. 2-D fields of angle-independent vector velocities are acquired
    using directional synthetic aperture vector flow imaging. The obtained results are evaluated by comparison to a
    3-D numerical simulation model with equivalent geometry as the designed phantom. The study showed pressure
    drops across the constricted phantom varying from -40 Pa to 15 Pa with a standard deviation of 32%, and a
    bias of 25% found relative to the peak simulated pressure drop. This preliminary study shows that pressure can
    be estimated non-invasively to a depth that enables cardiac scans, and thereby, the possibility of detecting the
    pressure drops across the mitral valve.
    Original languageEnglish
    Title of host publicationProceedings of SPIE
    EditorsNeb Duric, Brecht Heyde
    Number of pages6
    Volume9790
    PublisherSPIE - International Society for Optical Engineering
    Publication date2016
    Article number97900J
    DOIs
    Publication statusPublished - 2016
    EventSPIE Medical Imaging 2016 - Town & Country Resort and Convention Cente, San Diego, United States
    Duration: 27 Feb 20163 Mar 2016
    https://spie.org/conferences-and-exhibitions/past-conferences-and-exhibitions/medical-imaging-2016

    Conference

    ConferenceSPIE Medical Imaging 2016
    LocationTown & Country Resort and Convention Cente
    Country/TerritoryUnited States
    CitySan Diego
    Period27/02/201603/03/2016
    Internet address

    Keywords

    • Medical ultrasound
    • Pressure estimation
    • Vector flow imaging
    • Synthetic aperture

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