Lab-on-a-Chip (LoC) technologies require the possibility of fabricating devices which include micro down to sub-micrometre features with high production rate and low cost. In the present study precision injection moulding is performed using a COC Topas 5013 L10 polymer to produce LoC devices for DNA barcoding with functional features in the 100 nm to 10 μm range. Replication quality of produced features (from nickel to polymer) was assessed by calibrated atomic force microscope (AFM) measurements performed on multiple nanochannels test structures arrays placed at different positions in the sample. Design of experiment (DOE) was adopted to characterize the replication fidelity of produced polymer features. Results have shown the possibility of performing quality control of micro- and sub-μm features, taking into account the polymer shrinkage, depending on process conditions at both micro and nano dimensional scales.
|Title of host publication||Proceedings of the 15th International Conference of the European Society for Precision Engineering and Nanotechnology|
|Publisher||The European Society for Precision Engineering and Nanotechnology|
|Publication status||Published - 2015|
|Event||15th euspen International Conference & Exhibition (2015) - Leuven, Belgium|
Duration: 1 Jun 2015 → 5 Jun 2015
Conference number: 15
|Conference||15th euspen International Conference & Exhibition (2015)|
|Period||01/06/2015 → 05/06/2015|
Garnæs, J., Calaon, M., Tosello, G., Matusiewicz , K., & Hansen, H. N. (2015). Precision manufacturing of polymer micro-nano fluidic systems. In Proceedings of the 15th International Conference of the European Society for Precision Engineering and Nanotechnology (pp. 31-32). The European Society for Precision Engineering and Nanotechnology.