Precision manufacturing of polymer micro-nano fluidic systems

Jørgen Garnæs, Matteo Calaon, Guido Tosello, Krystian Matusiewicz , Hans N. Hansen

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review


Lab-on-a-Chip (LoC) technologies require the possibility of fabricating devices which include micro down to sub-micrometre features with high production rate and low cost. In the present study precision injection moulding is performed using a COC Topas 5013 L10 polymer to produce LoC devices for DNA barcoding with functional features in the 100 nm to 10 μm range. Replication quality of produced features (from nickel to polymer) was assessed by calibrated atomic force microscope (AFM) measurements performed on multiple nanochannels test structures arrays placed at different positions in the sample. Design of experiment (DOE) was adopted to characterize the replication fidelity of produced polymer features. Results have shown the possibility of performing quality control of micro- and sub-μm features, taking into account the polymer shrinkage, depending on process conditions at both micro and nano dimensional scales.
Original languageEnglish
Title of host publicationProceedings of the 15th International Conference of the European Society for Precision Engineering and Nanotechnology
PublisherThe European Society for Precision Engineering and Nanotechnology
Publication date2015
ISBN (Print)9780956679079
Publication statusPublished - 2015
Event15th euspen International Conference & Exhibition (2015) - Leuven, Belgium
Duration: 1 Jun 20155 Jun 2015
Conference number: 15


Conference15th euspen International Conference & Exhibition (2015)
Internet address


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