Polymeric cantilever-based biosensors with integrated readout

Alicia Johansson, Gabriela Blagoi, Anja Boisen

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    Abstract

    The authors present an SU-8 cantilever chip with integrated piezoresistors for detection of surface stress changes due to adsorption of biomolecules on the cantilever surface. Mercaptohexanol is used as a model biomolecule to study molecular interactions with Au-coated SU-8 cantilevers and surface stress changes of about 0.1 N/m are observed. The measurements indicate that the SU-8 surface is inert to mercaptohexanol molecules, which enables the use of a bare SU-8 cantilever as a reference. Moreover, the sensitivity of the cantilevers to pH changes is presented. The results demonstrate that SU-8 cantilevers are a promising alternative to Si-based cantilevers. (c) 2006 American Institute of Physics.
    Original languageEnglish
    JournalApplied Physics Letters
    Volume89
    Issue number17
    Pages (from-to)173505
    ISSN0003-6951
    DOIs
    Publication statusPublished - 2006

    Bibliographical note

    Copyright (2006) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

    Keywords

    • SENSORS

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