Polymer hydrogel capsules: en route toward synthetic cellular systems

Brigitte Staedler, Andrew D. Price, Rona Chandrawati, Leticia Hosta Rigau, Alexander N. Zelikin, Frank Caruso

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Abstract

Engineered synthetic cellular systems are expected to become a powerful biomedical platform For the development of next-generation therapeutic carrier Vehicles. In this mini-review, we discuss the potential of polymer capsules derived by the layer-by-layer assembly as it platform system for the construction of artificial cells and organelles. We Outline the characteristics of polymer capsules that make them unique for these applications, and we describe several Successful examples of microencapsulated catalysis, including biologically relevant enzymatic reactions. We also provide examples of subcompartmentalized polymer capsules, which represent a major step toward the creation of synthetic cells.
Original languageEnglish
JournalNanoscale
Volume1
Issue number1
Pages (from-to)68-73
Number of pages6
ISSN2040-3364
DOIs
Publication statusPublished - 2009
Externally publishedYes

Bibliographical note

This journal is © The Royal Society of Chemistry 2009

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