Polycaprolactone-templated reduced-graphene oxide liquid crystal nanofibers towards biomedical applications

Sasan Jalili-Firoozinezhad, Mohamad Hasan Mohamadzadeh Moghadam, Mohammad Hossein Ghanian, Mohammad Kazemi Ashtiani, Hossein Alimadadi, Hossein Baharvand, Ivan Martin, Arnaud Scherberich

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    Abstract

    Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO coating. We showed that coating the reduced GO (rGO) not only retains the three-dimensional topography, fiber orientation and size of the template PCL, but also makes it electroconductive. Our preliminary in vitro assessments using mesenchymal stem cells revealed no induced cytotoxicity yet increased cellular metabolism on PCL-templated rGO fibers.
    Original languageEnglish
    JournalR S C Advances
    Volume7
    Issue number63
    Pages (from-to)39628–39634
    ISSN2046-2069
    DOIs
    Publication statusPublished - 2017

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