Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl) quinic acid from Podospermum laciniatum (Asteraceae)

Christian Zidorn, Bent O. Petersen, Vedrana Udovicic ́, Thomas Ostenfeld Larsen, Jens Øllgaard Duus, Judith M. Rollinger, Karl-Hans Ongania, Ernst P. Ellmerer, Hermann Stuppner

    Research output: Contribution to journalJournal articleResearchpeer-review


    A phytochemical investigation of Podospermum laciniatum (L.) DC. (Asteraceae) yielded the new quinic acid derivative podospermic acid (1,3,5-tridihydrocaffeoylquinic acid), which was named after the genus it was isolated from. The structure was established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy. Podospermic acid is the first naturally occurring dihydrocaffeoylquinic acid derivative. The chemosystematic impact and the radical scavenging activity of the new compound are discussed briefly. (C) 2004 Elsevier Ltd. All rights reserved.
    Original languageEnglish
    JournalTetrahedron Letters
    Issue number8
    Pages (from-to)1291-1294
    Publication statusPublished - 2005


    • Science/technology
    • dihydrocaffeoylquinic acid
    • quinic acid
    • unclassified drug
    • analytic method
    • article
    • mass spectrometry
    • nuclear magnetic resonance spectroscopy
    • phytochemistry
    • Asteraceae
    • Cichorieae
    • Podospermum
    • Scorzonera laciniata
    • Natural products
    • Phenolics
    • Subtribe Scorzonerinae
    • Tribe Lactuceae
    • subtribe scorzonerinae
    • tribe lactuceae
    • asteraceae
    • natural products
    • phenolics


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