Picornavirus RNA translation: roles for cellular proteins

Graham Belsham, N. Sonenberg

Research output: Contribution to journalReviewResearchpeer-review

Abstract

Picornavirus RNA is translated within cells even when cellular cap-dependent protein synthesis is blocked. The efficiency of recognition of the viral RNA by the translational apparatus can determine viral tropism. The roles of cellular translation-initiation factors and other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.
Original languageEnglish
JournalTrends in Microbiology
Volume8
Issue number7
Pages (from-to)330-335
ISSN0966-842X
DOIs
Publication statusPublished - 2000
Externally publishedYes

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