Picornavirus RNA translation: roles for cellular proteins

Graham Belsham; N. Sonenberg

doi:10.1016/S0966-842X(00)01788-1

Picornavirus RNA translation: roles for cellular proteins

Graham Belsham, N. Sonenberg

Research output: Contribution to journal › Review › peer-review

Abstract

Picornavirus RNA is translated within cells even when cellular cap-dependent protein synthesis is blocked. The efficiency of recognition of the viral RNA by the translational apparatus can determine viral tropism. The roles of cellular translation-initiation factors and other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.

Original language	English
Journal	Trends in Microbiology
Volume	8
Issue number	7
Pages (from-to)	330-335
ISSN	0966-842X
DOIs	https://doi.org/10.1016/S0966-842X(00)01788-1
Publication status	Published - 2000
Externally published	Yes

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title = "Picornavirus RNA translation: roles for cellular proteins",

abstract = "Picornavirus RNA is translated within cells even when cellular cap-dependent protein synthesis is blocked. The efficiency of recognition of the viral RNA by the translational apparatus can determine viral tropism. The roles of cellular translation-initiation factors and other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.",

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AB - Picornavirus RNA is translated within cells even when cellular cap-dependent protein synthesis is blocked. The efficiency of recognition of the viral RNA by the translational apparatus can determine viral tropism. The roles of cellular translation-initiation factors and other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.

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DO - 10.1016/S0966-842X(00)01788-1

M3 - Review

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VL - 8

SP - 330

EP - 335

JO - Trends in Microbiology

JF - Trends in Microbiology

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Picornavirus RNA translation: roles for cellular proteins

Abstract

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