Photonic crystal fiber based evanescent-wave sensor for detection of biomolecules in aqueous solutions

Jesper Bo Damm Jensen, Lars H. Pedersen, Poul E. Hoiby, Lars B. Nielsen, Theis Peter Hansen, Jacob Riis Folkenberg, Jesper Riishede, Danny Noordegraaf, Kristian Nielsen, Anneline Carlsen, Anders Overgaard Bjarklev

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    We demonstrate highly efficient evanescent-wave detection of fluorophore-labeled biomolecules in aqueous solutions positioned in the air holes of the microstructured part of a photonic crystal fiber. The air-suspended silica structures located between three neighboring air holes in the cladding crystal guide light with a large fraction of the optical field penetrating into the sample even at wavelengths in the visible range. An effective interaction length of several centimeters is obtained when a sample volume of less than 1 µL is used.
    Original languageEnglish
    JournalOptics Letters
    Volume29
    Issue number17
    Pages (from-to)1974-1976
    ISSN1094-4087
    DOIs
    Publication statusPublished - 2004

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