Abstract
We demonstrate highly efficient evanescent-wave detection of fluorophore-labeled biomolecules in aqueous solutions positioned in the air holes of the microstructured part of a photonic crystal fiber. The air-suspended silica structures located between three neighboring air holes in the cladding crystal guide light with a large fraction of the optical field penetrating into the sample even at wavelengths in the visible range. An effective interaction length of several centimeters is obtained when a sample volume of less than 1 µL is used.
Original language | English |
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Journal | Optics Letters |
Volume | 29 |
Issue number | 17 |
Pages (from-to) | 1974-1976 |
ISSN | 1094-4087 |
DOIs | |
Publication status | Published - 2004 |