Photocatalytic Multicomponent Carboxylation of Olefins and Sulfinate Salts with 13CO2

Julien R. Lyonnet; Álvaro Velasco-Rubio; Roman Abrams; Ha Phan; Kim Mühlfenzl; Xuemeng Chen; Alessandro Cerveri; José Tiago M. Correia; Márcio W. Paixão; Charles S. Elmore; Ruben Martin

doi:10.1021/acscatal.4c06335

Photocatalytic Multicomponent Carboxylation of Olefins and Sulfinate Salts with ¹³CO₂

Julien R. Lyonnet
, Álvaro Velasco-Rubio
, Roman Abrams
, Ha Phan
, Kim Mühlfenzl
, Xuemeng Chen
, Alessandro Cerveri
, José Tiago M. Correia
, Márcio W. Paixão
, Charles S. Elmore
, Ruben Martin^*

^*Corresponding author for this work

Department of Chemistry

Universidad Rovira i Virgili
Institute of Chemical Research of Catalonia
Stockholm University
AstraZeneca
Universidade de São Paulo
Universidade Federal de São Carlos

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Herein, we describe a photoinduced multicomponent catalytic carboxylation protocol that streamlines the access to ¹³C-labeled carboxylic acids from simple olefin precursors, sulfinate salts and ¹³CO₂. Site selectivity is dictated by the radical philicity of the starting precursors and reaction intermediates, resulting in either a four-component or a five-component endeavor.

Original language	English
Journal	ACS Catalysis
Volume	14
Issue number	24
Pages (from-to)	18633-18638
ISSN	2155-5435
DOIs	https://doi.org/10.1021/acscatal.4c06335
Publication status	Published - 2024

Keywords

Carbon dioxide
Isotope labeling
Multicomponent
Olefins
Site selectivity

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10.1021/acscatal.4c06335

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Cite this

@article{b6fccd6cef6e4ab1ab4f8fb9bb4c2beb,

title = "Photocatalytic Multicomponent Carboxylation of Olefins and Sulfinate Salts with 13CO2",

abstract = "Herein, we describe a photoinduced multicomponent catalytic carboxylation protocol that streamlines the access to 13C-labeled carboxylic acids from simple olefin precursors, sulfinate salts and 13CO2. Site selectivity is dictated by the radical philicity of the starting precursors and reaction intermediates, resulting in either a four-component or a five-component endeavor.",

keywords = "Carbon dioxide, Isotope labeling, Multicomponent, Olefins, Site selectivity",

author = "Lyonnet, \{Julien R.\} and {\'A}lvaro Velasco-Rubio and Roman Abrams and Ha Phan and Kim M{\"u}hlfenzl and Xuemeng Chen and Alessandro Cerveri and Correia, \{Jos{\'e} Tiago M.\} and Paix{\~a}o, \{M{\'a}rcio W.\} and Elmore, \{Charles S.\} and Ruben Martin",

note = "Publisher Copyright: {\textcopyright} 2024 American Chemical Society.",

year = "2024",

doi = "10.1021/acscatal.4c06335",

language = "English",

volume = "14",

pages = "18633--18638",

journal = "ACS Catalysis",

issn = "2155-5435",

publisher = "American Chemical Society",

number = "24",

}

TY - JOUR

T1 - Photocatalytic Multicomponent Carboxylation of Olefins and Sulfinate Salts with 13CO2

AU - Lyonnet, Julien R.

AU - Velasco-Rubio, Álvaro

AU - Abrams, Roman

AU - Phan, Ha

AU - Mühlfenzl, Kim

AU - Chen, Xuemeng

AU - Cerveri, Alessandro

AU - Correia, José Tiago M.

AU - Paixão, Márcio W.

AU - Elmore, Charles S.

AU - Martin, Ruben

PY - 2024

Y1 - 2024

N2 - Herein, we describe a photoinduced multicomponent catalytic carboxylation protocol that streamlines the access to 13C-labeled carboxylic acids from simple olefin precursors, sulfinate salts and 13CO2. Site selectivity is dictated by the radical philicity of the starting precursors and reaction intermediates, resulting in either a four-component or a five-component endeavor.

AB - Herein, we describe a photoinduced multicomponent catalytic carboxylation protocol that streamlines the access to 13C-labeled carboxylic acids from simple olefin precursors, sulfinate salts and 13CO2. Site selectivity is dictated by the radical philicity of the starting precursors and reaction intermediates, resulting in either a four-component or a five-component endeavor.

KW - Carbon dioxide

KW - Isotope labeling

KW - Multicomponent

KW - Olefins

KW - Site selectivity

U2 - 10.1021/acscatal.4c06335

DO - 10.1021/acscatal.4c06335

M3 - Journal article

AN - SCOPUS:85211050978

SN - 2155-5435

VL - 14

SP - 18633

EP - 18638

JO - ACS Catalysis

JF - ACS Catalysis

IS - 24

ER -