Perspectives Across Data Holders, Tech Enablers, and Research Data Users in Trusted Research Environments

Trusted Research Environments (TREs) are essential for the secure use and sharing of sensitive health data, particularly within the framework of the European Health Data Space. They aim to balance robust data protection with efficient and transparent research access. Because TREs involve multiple stakeholder groups, including data holders, technical providers, and researchers, their successful implementation requires the integration of diverse perspectives. To capture these viewpoints, we organized a two-day international workshop with experts from academia, healthcare, and technology sectors. The discussions identified shared challenges related to user training and certification, harmonized access procedures, usability, billing, and data exchange. Addressing these issues collaboratively is crucial to developing effective and sustainable TREs that can advance data-driven health research across Europe.