Personalized Network-Based Treatments in Oncology

Xavier Robin, Pau Creixell, Oxana Radetskaya, Cristina Costa Santina, James Longden, Rune Linding

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Network medicine aims at unraveling cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technological and scientific developments in both drug design and signaling network analysis.
    Original languageEnglish
    JournalClinical Pharmacology and Therapeutics
    Volume94
    Issue number6
    Pages (from-to)646-650
    ISSN0009-9236
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Animals
    • Antineoplastic Combined chemotherapy protocols
    • Biological markers
    • Drug design
    • Individualized medicine
    • Molecular targeted therapy
    • Neoplasms
    • Protein interaction maps
    • Protein processing
    • post-translational modifications
    • Signal transduction
    • Systems biology

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