Abstract
A permeabilized whole cell catalyst and method for conversion (reducing the amount) of a target substrate to one of more product are provided, wherein the catalyst is obtained by incubating the cells with a permeabilization agent selected from a fatty acid and fatty acid derivative, and wherein the permeabilized cells comprise an intracellular enzyme for catalyzing conversion of the target substrate. The target substrate transits through the channel, holes, or pore made in the cell membrane by the permeabilization agent, and is converted to products by enzymes retained within the cell.
| Original language | English |
|---|---|
| IPC | C12P 19/ 02 A I |
| Patent number | WO2021239702 |
| Filing date | 25/05/2020 |
| Country/Territory | International Bureau of the World Intellectual Property Organization (WIPO) |
| Priority date | 25/05/2020 |
| Priority number | EP20200176344 |
| Publication status | Published - 2 Dec 2021 |