Abstract
Developmental thyroid hormone (TH) system disruption can adversely affect brain development. However, we lack methods to test environmental chemicals for their ability to affect brain development through TH system disruption. Here we show that neuroblasts, oligodendrocytes and parvalbumin-interneurons are among thecell types affected in different brain regions after perinatal TH deficiency. Further studies will determine if markers for these cell populations can be used in new test methods for the regulation of TH system disrupting chemicals in order to protect human health.
| Original language | English |
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| Publication date | 2022 |
| Number of pages | 1 |
| Publication status | Published - 2022 |
| Event | EURION (European cluster to improve identification of endocrine disruptors) Annual Meeting 2022 - Online Duration: 20 Jan 2022 → 21 Jan 2022 |
Conference
| Conference | EURION (European cluster to improve identification of endocrine disruptors) Annual Meeting 2022 |
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| Location | Online |
| Period | 20/01/2022 → 21/01/2022 |