Penicillium digitatum metabolites on synthetic media and citrus fruits

M.R. Ariza, Thomas Ostenfeld Larsen, Bent O. Petersen, Jens Øllgaard Duus, A.F. Barrero

    Research output: Contribution to journalJournal articleResearchpeer-review


    Penicillium digitatum has been cultured on citrus fruits and yeast extract sucrose agar media (YES).Cultivation of fungal cultures on solid medium allowed the isolation of two novel tryptoquivaline-like metabolites, tryptoquialanine A (1) and tryptoquialanine B (2), also biosynthesized on citrus fruits.Their structural elucidation is described on the basis of their spectroscopic data, including those from 2D NMR experiments. The analysis of the biomass sterols led to the identification of 8-12. Fungal infection on the natural substrates induced the release of citrus monoterpenes together with fungal volatiles. The host-pathogen interaction in nature and the possible biological role of citrus volatiles are also discussed
    Original languageEnglish
    JournalJournal of Agricultural and Food Chemistry
    Issue number22
    Pages (from-to)6361-6365
    Publication statusPublished - 2002


    • Citrus fruits
    • Penicillium digitatum
    • Quivaline metabolites
    • Tryptoquivaline
    • P. digitatum sterols
    • Phenylacetic acid derivatives
    • Volatile metabolites

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