Pattern formation: fruiting body morphogenesis in Myxococcus xanthus

Lars Jelsbak, L. Sogaard-Andersen

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When Myxococcus xanthus cells are exposed to starvation, they respond with dramatic behavioral changes. The expansive swarming behavior stops and the cells begin to aggregate into multicellular fruiting bodies. The cell-surface-associated C-signal has been identified as the signal that induces aggregation. Recently, several of the components in the C-signal transduction pathway have been identified and behavioral analyses are beginning to reveal how the C-signal modulates cell behavior. Together, these findings provide a framework for understanding how a cell-surface-associated morphogen induces pattern formation.
Original languageEnglish
JournalCurrent Opinion in Microbiology
Issue number6
Pages (from-to)637-642
Number of pages6
Publication statusPublished - 2000
Externally publishedYes


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