Abstract
In this work we present a novel automated system which allows the study of enzymatic degradation of biopolymer films coated on micromechanical resonators. The system combines an optical readout based on Blu-Ray technology with a software-controlled scanning mechanism. Integrated with a microfluidic setup unit, the system allows high-throughput measurements of resonance frequency over microresonator arrays under controlled flow conditions. We here demonstrate the acquisition of statistical data on biopolymer films degradation under enzymatic reaction over a large sample of micromechanical resonators. The system has been proved to be able to perform measurements both in air and in liquid environment.
| Original language | English |
|---|---|
| Title of host publication | 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 |
| Number of pages | 3 |
| Publisher | Chemical and Biological Microsystems Society |
| Publication date | 2015 |
| Pages | 1870-1872 |
| ISBN (Electronic) | 9780979806483 |
| Publication status | Published - 2015 |
| Event | 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Hwabaek International Convention Center, Gyeongju-si, Korea, Republic of Duration: 25 Oct 2015 → 29 Oct 2015 Conference number: 19 https://mtas.hdasan.com/ |
Conference
| Conference | 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|---|
| Number | 19 |
| Location | Hwabaek International Convention Center |
| Country/Territory | Korea, Republic of |
| City | Gyeongju-si |
| Period | 25/10/2015 → 29/10/2015 |
| Internet address |
Keywords
- Control and Systems Engineering
- Automation
- Biomolecules
- Resonators
- Blu-ray technology
- Enzymatic Degradation
- Enzymatic reaction
- High-throughput measurements
- Liquid environment
- Micro-resonator arrays
- Resonance frequencies
- Scanning mechanisms
- Micromechanical resonators