Packing of protein structures in clusters with magic numbers

Per-Anker Lindgård, Henrik Bohr

    Research output: Contribution to journalConference articleResearchpeer-review

    Abstract

    Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster. A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.
    Original languageEnglish
    JournalZeitschrift fur Physik D
    Volume40
    Issue number1-4
    Pages (from-to)236-239
    ISSN0178-7683
    DOIs
    Publication statusPublished - 1997
    Event8th International Symposium on Small Particles and Inorganic Clusters - Copenhagen, Denmark
    Duration: 1 Jul 19966 Jul 1996
    Conference number: 8
    http://www.springer.com/physics/atomic,+molecular,+optical+%26+plasma+physics/book/978-3-642-64586-0

    Conference

    Conference8th International Symposium on Small Particles and Inorganic Clusters
    Number8
    CountryDenmark
    CityCopenhagen
    Period01/07/199606/07/1996
    Internet address

    Fingerprint Dive into the research topics of 'Packing of protein structures in clusters with magic numbers'. Together they form a unique fingerprint.

    Cite this