Packing of protein structures in clusters with magic numbers

Per-Anker Lindgård; Henrik Bohr

doi:10.1007/s004600050201

Packing of protein structures in clusters with magic numbers

Per-Anker Lindgård, Henrik Bohr

Research output: Contribution to journal › Conference article › Research › peer-review

Abstract

Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster. A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.

Original language	English
Journal	Zeitschrift fur Physik D-Atoms Molecules and Clusters
Volume	40
Issue number	1-4
Pages (from-to)	236-239
ISSN	0178-7683
DOIs	https://doi.org/10.1007/s004600050201
Publication status	Published - 1997
Event	8th International Symposium on Small Particles and Inorganic Clusters - Copenhagen, Denmark Duration: 1 Jul 1996 → 6 Jul 1996 Conference number: 8 http://www.springer.com/physics/atomic,+molecular,+optical+%26+plasma+physics/book/978-3-642-64586-0

Conference

Conference	8th International Symposium on Small Particles and Inorganic Clusters
Number	8
Country/Territory	Denmark
City	Copenhagen
Period	01/07/1996 → 06/07/1996
Internet address	http://www.springer.com/physics/atomic,+molecular,+optical+%26+plasma+physics/book/978-3-642-64586-0

Access to Document

10.1007/s004600050201

OpenUrl availability

Full text

Cite this

@inproceedings{8539fae849ca41f0865d614ae7a83a48,

title = "Packing of protein structures in clusters with magic numbers",

abstract = "Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster. A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.",

keywords = "Nye funktionelle materialer",

author = "Per-Anker Lindg{\aa}rd and Henrik Bohr",

year = "1997",

doi = "10.1007/s004600050201",

language = "English",

volume = "40",

pages = "236--239",

journal = "Zeitschrift fur Physik D-Atoms Molecules and Clusters",

issn = "0178-7683",

publisher = "Springer Verlag",

number = "1-4",

note = "8th International Symposium on Small Particles and Inorganic Clusters, ISSPIC 8 ; Conference date: 01-07-1996 Through 06-07-1996",

url = "http://www.springer.com/physics/atomic,+molecular,+optical+%26+plasma+physics/book/978-3-642-64586-0",

}

TY - GEN

T1 - Packing of protein structures in clusters with magic numbers

AU - Lindgård, Per-Anker

AU - Bohr, Henrik

N1 - Conference code: 8

PY - 1997

Y1 - 1997

N2 - Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster. A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.

AB - Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster. A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.

KW - Nye funktionelle materialer

U2 - 10.1007/s004600050201

DO - 10.1007/s004600050201

M3 - Conference article

SN - 0178-7683

VL - 40

SP - 236

EP - 239

JO - Zeitschrift fur Physik D-Atoms Molecules and Clusters

JF - Zeitschrift fur Physik D-Atoms Molecules and Clusters

IS - 1-4

T2 - 8th International Symposium on Small Particles and Inorganic Clusters

Y2 - 1 July 1996 through 6 July 1996

ER -

Packing of protein structures in clusters with magic numbers

Abstract

Conference

Access to Document

OpenUrl availability

Fingerprint

Cite this