Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster. A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.
|Journal||Zeitschrift fur Physik D|
|Publication status||Published - 1997|
|Event||8th International Symposium on Small Particles and Inorganic Clusters - Copenhagen, Denmark|
Duration: 1 Jul 1996 → 6 Jul 1996
Conference number: 8
|Conference||8th International Symposium on Small Particles and Inorganic Clusters|
|Period||01/07/1996 → 06/07/1996|