Abstract
Biocatalytic oxidation reactions offer several important benefits such as regio- and stereoselectivity, avoiding the use of toxic metal based catalysts and replacing oxidizing reagents by allowing the use of oxygen. In this contribution the oxygen requirements are analysed for different process scenarios, considering different biocatalyst formats and variation of the desired productivity. Also, the applicability of two different oxygen supply methods (bubbling and membrane aeration) is considered. The results indicate that growing cells could be used to reach productivities up to 3.5 g L-1h-1 without oxygen supply being limiting. Also, membrane contactors can provide a feasible oxygen supply method when bubble-less aeration is desired. However, in order to support high productivity the oxygen flux using air may be insufficient, thus requiring the use of oxygen.
Original language | English |
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Title of host publication | Proceedings of the 25th European Symposium on Computer Aided Process Engineering |
Editors | Krist V. Gernaey, Jakob K. Huusom, Rafiqul Gani |
Number of pages | 6 |
Volume | 37 |
Publisher | Elsevier |
Publication date | 2015 |
Pages | 2111-2116 |
DOIs | |
Publication status | Published - 2015 |
Event | 25th European Symposium on Computer Aided Process Engineering : 12th International Symposium on Process Systems Engineering - Copenhagen, Denmark Duration: 31 May 2015 → 4 Jun 2015 http://www.pse2015escape25.dk/ |
Conference
Conference | 25th European Symposium on Computer Aided Process Engineering |
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Country/Territory | Denmark |
City | Copenhagen |
Period | 31/05/2015 → 04/06/2015 |
Internet address |
Series | Computer Aided Chemical Engineering |
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ISSN | 1570-7946 |
Keywords
- Biocatalysis
- Oxygen requirements
- Oxygen supply