Biocatalytic oxidation reactions offer several important benefits such as regio- and stereoselectivity, avoiding the use of toxic metal based catalysts and replacing oxidizing reagents by allowing the use of oxygen. However, the development of biocatalytic oxidation processes is a complex task which requires simultaneous consideration of several issues regarding the process design and operation. In this work, the oxygen requirements are analysed for different process scenarios, considering different biocatalyst formats and variation of the desired productivity. Also, the applicability of two different oxygen supply methods (bubbling and membrane aeration) investigated. Hollow fibre membrane contactors present an interesting alternative for reactor aeration, creating large specific areas (area/volume) of the gas/liquid interface. The modular design of membrane contactors, scaling-up is relatively straight forward (Gabelman and Hwang, 1999), and membrane contactors are implemented for various industrial applications (Klaassen et al., 2005).
|Number of pages||1|
|Publication status||Published - 2015|
|Event||Towards P450 Applications: FP7 PEOPLE P4FIFTY ITN (Initial Training Network) Conference - Le Bischenberg, Bischoffsheim, France|
Duration: 24 Jun 2015 → 26 Jun 2015
|Conference||Towards P450 Applications|
|Period||24/06/2015 → 26/06/2015|