Outbreak of Pasteurella pneumotropica in a closed colony of STOCK-Cd28(tm1Mak) mice

J.E. Artwohl, J.C. Flynn, R.M. Bunte, Øystein Angen, K.C. Herold

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Fifteen mice with Pasteurella pneumotropica orbital abscesses were noted in mice that were homozygous for a targeted Cd28 gene mutation. Only one mouse heterozygous for the Cd28 mutation was affected. According to phenotypic reactions and 16S rDNA sequencing, the isolates were most similar to biotype Heyl, This article provides evidence for an immunologic basis of susceptibility to P. pneumotropica infection.
    Original languageEnglish
    JournalContemporary topics in laboratory animal science
    Volume39
    Issue number1
    Pages (from-to)39-41
    ISSN1060-0558
    Publication statusPublished - 2000

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