Optomagnetic studies of ph-switchable nanoparticle agglutination via triplex dna formation

Gabriel Khose Antonio Minero; Jeppe Fock; J.S. McCaskill; Mikkel Fougt Hansen

Optomagnetic studies of ph-switchable nanoparticle agglutination via triplex dna formation

Gabriel Khose Antonio Minero, Jeppe Fock, J.S. McCaskill, Mikkel Fougt Hansen

Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review

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Abstract

Polypurine-polypyrimidine sequences found in eukaryotic genomes can fold into a triple-helical structure if the sequences exhibit mirror symmetry [1]. They have been shown to stop DNA replication in vitro and in cell cultures and play a significant role in genetic regulation. New methods are needed to investigate switching behavior of triplex DNA complexes under controlled conditions.

Original language	English
Title of host publication	Proceedings of Microtas 2016
Number of pages	2
Publication date	2016
Publication status	Published - 2016
Event	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences: MicroTAS 2016 - Dublin, Ireland Duration: 9 Oct 2016 → 13 Oct 2016 Conference number: 20 http://www.microtas2016.org/

Conference

Conference	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number	20
Country	Ireland
City	Dublin
Period	09/10/2016 → 13/10/2016
Internet address	http://www.microtas2016.org/

Keywords

DNA triplex
Nanaoparticle
Biosensor
pH

Access to Document

Minero TAS proceedingsAccepted author manuscript, 748 KB

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Cite this

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title = "Optomagnetic studies of ph-switchable nanoparticle agglutination via triplex dna formation",

abstract = "Polypurine-polypyrimidine sequences found in eukaryotic genomes can fold into a triple-helical structure if the sequences exhibit mirror symmetry [1]. They have been shown to stop DNA replication in vitro and in cell cultures and play a significant role in genetic regulation. New methods are needed to investigate switching behavior of triplex DNA complexes under controlled conditions.",

keywords = "DNA triplex, Nanaoparticle, Biosensor, pH",

author = "Minero, {Gabriel Khose Antonio} and Jeppe Fock and J.S. McCaskill and Hansen, {Mikkel Fougt}",

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language = "English",

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T1 - Optomagnetic studies of ph-switchable nanoparticle agglutination via triplex dna formation

AU - Minero, Gabriel Khose Antonio

AU - Fock, Jeppe

AU - McCaskill, J.S.

AU - Hansen, Mikkel Fougt

N1 - Conference code: 20

PY - 2016

Y1 - 2016

N2 - Polypurine-polypyrimidine sequences found in eukaryotic genomes can fold into a triple-helical structure if the sequences exhibit mirror symmetry [1]. They have been shown to stop DNA replication in vitro and in cell cultures and play a significant role in genetic regulation. New methods are needed to investigate switching behavior of triplex DNA complexes under controlled conditions.

AB - Polypurine-polypyrimidine sequences found in eukaryotic genomes can fold into a triple-helical structure if the sequences exhibit mirror symmetry [1]. They have been shown to stop DNA replication in vitro and in cell cultures and play a significant role in genetic regulation. New methods are needed to investigate switching behavior of triplex DNA complexes under controlled conditions.

KW - DNA triplex

KW - Nanaoparticle

KW - Biosensor

KW - pH

M3 - Conference abstract in proceedings

BT - Proceedings of Microtas 2016

T2 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 9 October 2016 through 13 October 2016

ER -