Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

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Abstract

We report an in-depth analysis and a fabrication method to precisely produce micro-sized arrays of supercritical angle fluorescence optical structures in disposal microfluidic polymer chips. This technique can be used for industrially massive production of disposal microfluidic polymer chips for pathogen detections with application in food safety and clinical diagnosis. For a demonstration, the chip is used to successfully detect E. coli with the limit of detection of 3.37 x 102 copies.
Original languageEnglish
Title of host publicationProceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences
Place of PublicationKaohsiung, Taiwan
Publication date2018
Pages2284-2285
ISBN (Electronic)978-0-578-40530-8
Publication statusPublished - 2018
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences - Kaohsiung Exhibition Center, Kaohsiung, Taiwan, Province of China
Duration: 11 Nov 201815 Nov 2018
Conference number: 22
https://cbmsociety.org/conferences/microtas2018/

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number22
LocationKaohsiung Exhibition Center
CountryTaiwan, Province of China
CityKaohsiung
Period11/11/201815/11/2018
Internet address

Keywords

  • microfluidics
  • pathogen detections
  • diagnosis
  • polymer injection molding
  • fluorescence
  • PCR

Cite this

Nguyen, T., Ngo Anh, T., Wolff, A., & Bang, D. D. (2018). Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection. In Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2284-2285). Kaohsiung, Taiwan.
Nguyen, Trieu ; Ngo Anh, Tien ; Wolff, Anders ; Bang, Dang Duong. / Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection. Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Kaohsiung, Taiwan, 2018. pp. 2284-2285
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abstract = "We report an in-depth analysis and a fabrication method to precisely produce micro-sized arrays of supercritical angle fluorescence optical structures in disposal microfluidic polymer chips. This technique can be used for industrially massive production of disposal microfluidic polymer chips for pathogen detections with application in food safety and clinical diagnosis. For a demonstration, the chip is used to successfully detect E. coli with the limit of detection of 3.37 x 102 copies.",
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Nguyen, T, Ngo Anh, T, Wolff, A & Bang, DD 2018, Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection. in Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Kaohsiung, Taiwan, pp. 2284-2285, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, Kaohsiung, Taiwan, Province of China, 11/11/2018.

Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection. / Nguyen, Trieu; Ngo Anh, Tien; Wolff, Anders; Bang, Dang Duong.

Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Kaohsiung, Taiwan, 2018. p. 2284-2285.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

TY - ABST

T1 - Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection

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AU - Wolff, Anders

AU - Bang, Dang Duong

PY - 2018

Y1 - 2018

N2 - We report an in-depth analysis and a fabrication method to precisely produce micro-sized arrays of supercritical angle fluorescence optical structures in disposal microfluidic polymer chips. This technique can be used for industrially massive production of disposal microfluidic polymer chips for pathogen detections with application in food safety and clinical diagnosis. For a demonstration, the chip is used to successfully detect E. coli with the limit of detection of 3.37 x 102 copies.

AB - We report an in-depth analysis and a fabrication method to precisely produce micro-sized arrays of supercritical angle fluorescence optical structures in disposal microfluidic polymer chips. This technique can be used for industrially massive production of disposal microfluidic polymer chips for pathogen detections with application in food safety and clinical diagnosis. For a demonstration, the chip is used to successfully detect E. coli with the limit of detection of 3.37 x 102 copies.

KW - microfluidics

KW - pathogen detections

KW - diagnosis

KW - polymer injection molding

KW - fluorescence

KW - PCR

M3 - Conference abstract in proceedings

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EP - 2285

BT - Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences

CY - Kaohsiung, Taiwan

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Nguyen T, Ngo Anh T, Wolff A, Bang DD. Optimizing supercritical angle fluorescence structures in polymer microfluidic chips for highly sensitive pathogen detection. In Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Kaohsiung, Taiwan. 2018. p. 2284-2285