Abstract
| Original language | English |
|---|---|
| Journal | Journal of Magnetic Resonance |
| Volume | 305 |
| Pages (from-to) | 58-65 |
| Number of pages | 8 |
| ISSN | 1090-7807 |
| DOIs | |
| Publication status | Published - 2019 |
Keywords
- Disssolution-DNP
- Microwave
- Electromagnetic simulation
- Solid-state NMR
Cite this
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Optimized microwave delivery in dDNP. / Albannay, Mohammed M.; M.O. Vinther, Joachim; Capozzi, Andrea; Zhurbenko, Vitaliy; Ardenkjær-Larsen, Jan Henrik.
In: Journal of Magnetic Resonance, Vol. 305, 2019, p. 58-65.Research output: Contribution to journal › Journal article › Research › peer-review
TY - JOUR
T1 - Optimized microwave delivery in dDNP
AU - Albannay, Mohammed M.
AU - M.O. Vinther, Joachim
AU - Capozzi, Andrea
AU - Zhurbenko, Vitaliy
AU - Ardenkjær-Larsen, Jan Henrik
PY - 2019
Y1 - 2019
N2 - Dissolution dynamic nuclear polarization (dDNP) has permitted the production of highly polarized liquid-state samples enabling real-time imaging of metabolic processes non-invasively in vivo. The desire for higher magnetic resonance sensitivity has led to the development of multiple home-built and commercial dDNP polarizers employing solid-state microwave sources. Providing efficient microwave delivery that avoids unwanted heating of the sample is a crucial step to achieve high nuclear polarization. Consequently, a process is described to reduce waveguide attenuation due to resistive loss thereby doubling the delivered power. A mirror and reflector are designed and tested to increase the microwave field density across the sample volume resulting in a 2.3 dB increase of delivered power. Thermal considerations with regards to waveguide geometry and dDNP probe design are discussed. A thermal model of the dDNP probe is computed and experimentally verified.
AB - Dissolution dynamic nuclear polarization (dDNP) has permitted the production of highly polarized liquid-state samples enabling real-time imaging of metabolic processes non-invasively in vivo. The desire for higher magnetic resonance sensitivity has led to the development of multiple home-built and commercial dDNP polarizers employing solid-state microwave sources. Providing efficient microwave delivery that avoids unwanted heating of the sample is a crucial step to achieve high nuclear polarization. Consequently, a process is described to reduce waveguide attenuation due to resistive loss thereby doubling the delivered power. A mirror and reflector are designed and tested to increase the microwave field density across the sample volume resulting in a 2.3 dB increase of delivered power. Thermal considerations with regards to waveguide geometry and dDNP probe design are discussed. A thermal model of the dDNP probe is computed and experimentally verified.
KW - Disssolution-DNP
KW - Microwave
KW - Electromagnetic simulation
KW - Solid-state NMR
U2 - 10.1016/j.jmr.2019.06.004
DO - 10.1016/j.jmr.2019.06.004
M3 - Journal article
VL - 305
SP - 58
EP - 65
JO - Journal of Magnetic Resonance
JF - Journal of Magnetic Resonance
SN - 1090-7807
ER -