Optimized microwave delivery in dDNP

Mohammed M. Albannay, Joachim M.O. Vinther, Andrea Capozzi, Vitaliy Zhurbenko, Jan Henrik Ardenkjær-Larsen*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Dissolution dynamic nuclear polarization (dDNP) has permitted the production of highly polarized liquid-state samples enabling real-time imaging of metabolic processes non-invasively in vivo. The desire for higher magnetic resonance sensitivity has led to the development of multiple home-built and commercial dDNP polarizers employing solid-state microwave sources. Providing efficient microwave delivery that avoids unwanted heating of the sample is a crucial step to achieve high nuclear polarization. Consequently, a process is described to reduce waveguide attenuation due to resistive loss thereby doubling the delivered power. A mirror and reflector are designed and tested to increase the microwave field density across the sample volume resulting in a 2.3 dB increase of delivered power. Thermal considerations with regards to waveguide geometry and dDNP probe design are discussed. A thermal model of the dDNP probe is computed and experimentally verified.
Original languageEnglish
JournalJournal of Magnetic Resonance
Pages (from-to)58-65
Number of pages8
Publication statusPublished - 2019


  • Disssolution-DNP
  • Microwave
  • Electromagnetic simulation
  • Solid-state NMR


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