Optimal operation of parallel dead-end filters in a continuous bio-based process

Research output: Contribution to journalJournal article – Annual report year: 2019Researchpeer-review

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Dead-end cake filtration as one of the first unit operations deployed in biochemical production plants has been subject of academic investigation for many decades. The recurrent discrete reinitialisation events are challenging from a process control point of view, especially in a continuous downstream line. The complexity that arises when multiple units are operated in parallel seems to have received little attention. This work aims at illustrating this complexity and delineates the arising plantwide control problem. Guidelines for optimised operation are derived from general process understanding and at hand of an industrial case study. The need for a predictive model to solve multiple scheduling problems is identified, and a mathematical model based on conventional filtration theory is derived. Due to raw material variability and operational uncertainties, the predictions are found to be too imprecise for deployment. This is expected to be representative of many bio-based processes, where manual scheduling needs to be integrated effectively into plantwide control structures.
Original languageEnglish
JournalFood and Bioproducts Processing
Pages (from-to)263-275
Publication statusPublished - 2019
CitationsWeb of Science® Times Cited: No match on DOI

    Research areas

  • Biological raw material, Dead-end filtration, Downstream line, Full-Scale process, Industrial case study, Plantwide control

ID: 170470324