Optical coherence tomography: Technique and applications

Jakob Borup Thomsen, Birgit Sander, Mette Mogensen, Lars Thrane, Thomas Martini Jørgensen, Gregor B.E. Jemec, Peter E. Andersen

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Abstract

Optical coherence tomography (OCT) is a noninvasive optical imaging modality providing real-time video rate images in two and three dimensions of biological tissues with micrometer resolution. OCT fills the gap between ultrasound and confocal microscopy, since it has a higher resolution than ultrasound and a higher penetration than confocal microcopy. Functional extensions are also possible, i.e., flow, birefringence or spectroscopic measurements with high spatial resolution. In ophthalmology, OCT is accepted as a clinical standard for diagnosing and monitoring the treatment of a number of retinal diseases. The potential of OCT in many other applications is currently being explored, such as in developmental biology, skin cancer diagnostics, vulnerable plaque detection in cardiology, esophageal diagnostics and a number of other applications within oncology.
Original languageEnglish
Title of host publicationAdvanced Imaging in Biology and Medicine : Technology, Software Environments, Applications
EditorsC.W. Sensen, B. Hallgrimsson
Number of pages445
Place of PublicationBerlin
PublisherSpringer
Publication date2009
Pages103-130
Chapter5
ISBN (Print)978-3-540-68992-8
ISBN (Electronic)978-3-540-68993-5
DOIs
Publication statusPublished - 2009

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