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Optical coherence tomography in clinical examinations of nonpigmented skin malignancies

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

    Abstract

    Optical coherence tomography (OCT) images of basal cell carcinomas (BCCs) have been acquired using a compact handheld probe with an integrated video camera allowing the OCT images to be correlated to a skin surface image. In general the healthy tissue of the skin has an obvious stratified structure, whereas the cancerous tissue shows a more homogenous structure. Thus it was demonstrated that it is possible to distinguish BCCs from healthy tissue by means of OCT. Furthermore different histological types of BCC were identified. Comparison of OCT images taken prior to and immediately after photodynamic therapy clearly shows the tissue response to the treatment, and indicates local oedema in the treated area.
    Original languageEnglish
    Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
    EditorsW. Drexler
    Volume5140
    Place of PublicationBellingham, WA
    PublisherThe International Society for Optical Engineering
    Publication date2003
    Pages160-167
    ISBN (Print)0-8194-5010-3
    DOIs
    Publication statusPublished - 2003
    EventConference on Optical Coherence Tomography and Coherence Techniques - Munich, Germany
    Duration: 22 Jun 200324 Jun 2003

    Conference

    ConferenceConference on Optical Coherence Tomography and Coherence Techniques
    Country/TerritoryGermany
    CityMunich
    Period22/06/200324/06/2003
    SeriesSPIE Proceedings Series, 5140

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