Only small fractions of soluble ß-glucan modulate the mucosal immune system in carp (Cyprinus carpio L.)

Dominika Alicja Przybylska, Michael Engelbrecht Nielsen

Research output: Contribution to conferencePosterResearch

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Abstract

For decades the ability of β-glucans to modulate immunity through activation of innate cellular components has been observed. However, toxicological effects associated with the systemic administration and dose-related immune-suppression has also been described. The superior aim of this study is to understand the effect of β-glucan induced modulation in carp in relation to tissue regeneration, mucosal immunity and host-pathogen interactions. Expression profiles of immune related genes will be measured in fresh water specie – common carp (Cyprinus carpio L.). The methodology of the project involves the usage of real-time quantitative PCR to quantify expression of genes of interest (IL-1β, IL-10, TNF-α, IL-6). This study will provide further understanding on the effect of β-glucan as a modulator which could improve fish welfare and health as well as having an economic potential production for the aquaculture industry.
Original languageEnglish
Publication date2011
Publication statusPublished - 2011
Event12th Fish Immunology Workshop - Wageningen, Netherlands
Duration: 11 Apr 201015 Apr 2010

Conference

Conference12th Fish Immunology Workshop
CountryNetherlands
CityWageningen
Period11/04/201015/04/2010

Cite this

Przybylska, D. A., & Nielsen, M. E. (2011). Only small fractions of soluble ß-glucan modulate the mucosal immune system in carp (Cyprinus carpio L.). Poster session presented at 12th Fish Immunology Workshop, Wageningen, Netherlands.