TY - JOUR
T1 - Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024
AU - Masirika, Leandre Murhula
AU - Udahemuka, Jean Claude
AU - Schuele, Leonard
AU - Ndishimye, Pacifique
AU - Otani, Saria
AU - Mbiribindi, Justin Bengehya
AU - Marekani, Jean M.
AU - Mambo, Léandre Mutimbwa
AU - Bubala, Nadine Malyamungu
AU - Boter, Marjan
AU - Nieuwenhuijse, David F.
AU - Lang, Trudie
AU - Kalalizi, Ernest Balyahamwabo
AU - Musabyimana, Jean Pierre
AU - Aarestrup, Frank M.
AU - Koopmans, Marion
AU - Oude Munnink, Bas B
AU - Siangoli, Freddy Belesi
PY - 2024
Y1 - 2024
N2 - Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South Kivu province. Phylogenetic analyses reveal that the MPXV affecting the cases belongs to a novel Clade I sub-lineage. The outbreak strain genome lacks the target sequence of the probe and primers of a commonly used Clade I-specific real-time PCR.
AB - Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South Kivu province. Phylogenetic analyses reveal that the MPXV affecting the cases belongs to a novel Clade I sub-lineage. The outbreak strain genome lacks the target sequence of the probe and primers of a commonly used Clade I-specific real-time PCR.
KW - Democratic Republic of the Congo
KW - Genomics
KW - Monkeypox virus
KW - mpox
KW - Surveillance
U2 - 10.2807/1560-7917.ES.2024.29.11.2400106
DO - 10.2807/1560-7917.ES.2024.29.11.2400106
M3 - Letter
C2 - 38487886
SN - 1025-496X
VL - 29
JO - Eurosurveillance
JF - Eurosurveillance
IS - 11
ER -