Abstract
The osmotic second virial coefficient is a key parameter in light scattering. protein crystallisation. self-interaction chromatography, and osmometry. The interpretation of the osmotic second virial coefficient depends on the solution theory. On the macroscopic level an expansion of the osmotic pressure is employed. A common statistical interpretation of the osmotic second virial coefficient of the expansion employs the McMillan-Mayer framework and the potential of mean force to characterise the solute-solute interaction. Supplementary to the statistical interpretation. it may be advantageous to develop the McMillan-Mayer framework in a classical thermodynamic context for which we develop the relationship between the state function of the McMillan-Mayer framework and the Helmholtz state function. A Taylor expansion method can be applied to the osmotic pressure of a solution which is dilute with respect to at least one solute component. This offers the possibility for an interpretation and correlation of the osmotic second virial coefficient utilising a McMillan-Mayer state function derived from a Helmholtz state function.
Original language | English |
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Journal | Fluid Phase Equilibria |
Volume | 276 |
Issue number | 1 |
Pages (from-to) | 18-23 |
ISSN | 0378-3812 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- Helmholtz state function
- McMillan-Mayer
- Potential of mean force
- Osmotic second virial coefficient
- Osmotic pressure