Abstract
| Original language | English |
|---|---|
| Journal | Journal of Magnetic Resonance |
| Volume | 264 |
| Pages (from-to) | 3-12 |
| ISSN | 1090-7807 |
| DOIs | |
| Publication status | Published - 2016 |
Keywords
- Biophysics
- Biochemistry
- Nuclear and High Energy Physics
- Condensed Matter Physics
- Dissolution-DNP
- Hyperpolarization
- Polarizer
- Dissolution
- Polarization
- Temperature
- Dissolution DNP
- Metabolic imaging
- Nuclear-spin polarization
- Orders of magnitude
- Signal enhancement
- Solid state dynamics
- Spin polarization
- Magnetic resonance spectrometers, auxiliary instruments and techniques
- dynamic nuclear polarisation
- magnetic resonance imaging
- dissolution-DNP
- nuclear spin polarization
- magnitude signal enhancement
- MR metabolic imaging
- solid state dynamic nuclear polarization
- BIOCHEMICAL
- PHYSICS,
- SPECTROSCOPY
- DYNAMIC-NUCLEAR-POLARIZATION
- LIQUID-STATE NMR
- PARA-HYDROGEN
- SENSITIVITY
- PERFORMANCE
- RESONANCE
- INJECTION
- MRI
- HYPERPOLARIZATION
Cite this
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On the present and future of dissolution-DNP. / Ardenkjær-Larsen, Jan Henrik.
In: Journal of Magnetic Resonance, Vol. 264, 2016, p. 3-12.Research output: Contribution to journal › Journal article › Research › peer-review
TY - JOUR
T1 - On the present and future of dissolution-DNP
AU - Ardenkjær-Larsen, Jan Henrik
PY - 2016
Y1 - 2016
N2 - Dissolution-DNP is a method to create solutions of molecules with nuclear spin polarization close to unity. The many orders of magnitude signal enhancement have enabled many new applications, in particular in vivo MR metabolic imaging. The method relies on solid state dynamic nuclear polarization at low temperature followed by a dissolution to produce the room temperature solution of highly polarized spins. This work describes the present and future of dissolution-DNP in the mind of the author. The article describes some of the current trends in the field as well as outlines some of the areas where new ideas will make an impact. Most certainly, the future will take unpredicted directions, but hopefully the thoughts presented here will stimulate new ideas that can further advance the field. (C) 2016 Elsevier Inc. All rights reserved.
AB - Dissolution-DNP is a method to create solutions of molecules with nuclear spin polarization close to unity. The many orders of magnitude signal enhancement have enabled many new applications, in particular in vivo MR metabolic imaging. The method relies on solid state dynamic nuclear polarization at low temperature followed by a dissolution to produce the room temperature solution of highly polarized spins. This work describes the present and future of dissolution-DNP in the mind of the author. The article describes some of the current trends in the field as well as outlines some of the areas where new ideas will make an impact. Most certainly, the future will take unpredicted directions, but hopefully the thoughts presented here will stimulate new ideas that can further advance the field. (C) 2016 Elsevier Inc. All rights reserved.
KW - Biophysics
KW - Biochemistry
KW - Nuclear and High Energy Physics
KW - Condensed Matter Physics
KW - Dissolution-DNP
KW - Hyperpolarization
KW - Polarizer
KW - Dissolution
KW - Polarization
KW - Temperature
KW - Dissolution DNP
KW - Metabolic imaging
KW - Nuclear-spin polarization
KW - Orders of magnitude
KW - Signal enhancement
KW - Solid state dynamics
KW - Spin polarization
KW - Magnetic resonance spectrometers, auxiliary instruments and techniques
KW - dynamic nuclear polarisation
KW - magnetic resonance imaging
KW - dissolution-DNP
KW - nuclear spin polarization
KW - magnitude signal enhancement
KW - MR metabolic imaging
KW - solid state dynamic nuclear polarization
KW - BIOCHEMICAL
KW - PHYSICS,
KW - SPECTROSCOPY
KW - DYNAMIC-NUCLEAR-POLARIZATION
KW - LIQUID-STATE NMR
KW - PARA-HYDROGEN
KW - SENSITIVITY
KW - PERFORMANCE
KW - RESONANCE
KW - INJECTION
KW - MRI
KW - HYPERPOLARIZATION
U2 - 10.1016/j.jmr.2016.01.015
DO - 10.1016/j.jmr.2016.01.015
M3 - Journal article
C2 - 26920825
VL - 264
SP - 3
EP - 12
JO - Journal of Magnetic Resonance
JF - Journal of Magnetic Resonance
SN - 1090-7807
ER -