On-chip measurement of the Brownian relaxation frequency of magnetic beads using magnetic tunneling junctions

M. Donolato; E. Sogne; Bjarke Thomas Dalslet; M. Cantoni; D. Petti; J. Cao; F. Cardoso; S. Cardoso; P. P. Freitas; Mikkel Fougt Hansen; R. Bertacco

doi:10.1063/1.3554374

On-chip measurement of the Brownian relaxation frequency of magnetic beads using magnetic tunneling junctions

M. Donolato, E. Sogne, Bjarke Thomas Dalslet, M. Cantoni, D. Petti, J. Cao, F. Cardoso, S. Cardoso, P. P. Freitas, Mikkel Fougt Hansen, R. Bertacco

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Abstract

We demonstrate the detection of the Brownian relaxation frequency of 250 nm diameter magnetic beads using a lab-on-chip platform based on current lines for exciting the beads with alternating magnetic fields and highly sensitive magnetic tunnel junction (MTJ) sensors with a superparamagnetic free layer. The first harmonic out-of-phase component of the MTJ response gives the imaginary part of the magnetic bead susceptibility, which peaks at the Brownian relaxation frequency. This work paves the way to on-chip implementation of Brownian magnetorelaxometry in innovative "lab-on-a-bead" assays for biomolecular recognition. (C) 2011 American Institute of Physics. [doi:10.1063/1.3554374]

Original language	English
Journal	Applied Physics Letters
Volume	98
Issue number	7
Pages (from-to)	073702
ISSN	0003-6951
DOIs	https://doi.org/10.1063/1.3554374
Publication status	Published - 2011

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ApplPhysLett 98 073702[1]Final published version, 579 KB

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abstract = "We demonstrate the detection of the Brownian relaxation frequency of 250 nm diameter magnetic beads using a lab-on-chip platform based on current lines for exciting the beads with alternating magnetic fields and highly sensitive magnetic tunnel junction (MTJ) sensors with a superparamagnetic free layer. The first harmonic out-of-phase component of the MTJ response gives the imaginary part of the magnetic bead susceptibility, which peaks at the Brownian relaxation frequency. This work paves the way to on-chip implementation of Brownian magnetorelaxometry in innovative {"}lab-on-a-bead{"} assays for biomolecular recognition. (C) 2011 American Institute of Physics. [doi:10.1063/1.3554374]",

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T1 - On-chip measurement of the Brownian relaxation frequency of magnetic beads using magnetic tunneling junctions

AU - Donolato, M.

AU - Sogne, E.

AU - Dalslet, Bjarke Thomas

AU - Cantoni, M.

AU - Petti, D.

AU - Cao, J.

AU - Cardoso, F.

AU - Cardoso, S.

AU - Freitas, P. P.

AU - Hansen, Mikkel Fougt

AU - Bertacco, R.

PY - 2011

Y1 - 2011

N2 - We demonstrate the detection of the Brownian relaxation frequency of 250 nm diameter magnetic beads using a lab-on-chip platform based on current lines for exciting the beads with alternating magnetic fields and highly sensitive magnetic tunnel junction (MTJ) sensors with a superparamagnetic free layer. The first harmonic out-of-phase component of the MTJ response gives the imaginary part of the magnetic bead susceptibility, which peaks at the Brownian relaxation frequency. This work paves the way to on-chip implementation of Brownian magnetorelaxometry in innovative "lab-on-a-bead" assays for biomolecular recognition. (C) 2011 American Institute of Physics. [doi:10.1063/1.3554374]

AB - We demonstrate the detection of the Brownian relaxation frequency of 250 nm diameter magnetic beads using a lab-on-chip platform based on current lines for exciting the beads with alternating magnetic fields and highly sensitive magnetic tunnel junction (MTJ) sensors with a superparamagnetic free layer. The first harmonic out-of-phase component of the MTJ response gives the imaginary part of the magnetic bead susceptibility, which peaks at the Brownian relaxation frequency. This work paves the way to on-chip implementation of Brownian magnetorelaxometry in innovative "lab-on-a-bead" assays for biomolecular recognition. (C) 2011 American Institute of Physics. [doi:10.1063/1.3554374]

U2 - 10.1063/1.3554374

DO - 10.1063/1.3554374

M3 - Journal article

VL - 98

SP - 073702

JO - Applied Physics Letters

JF - Applied Physics Letters

SN - 0003-6951

IS - 7

ER -

On-chip measurement of the Brownian relaxation frequency of magnetic beads using magnetic tunneling junctions

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