Oligonucleotide Probes That Detect Quantitatively Significant Groups of Butyrate-Producing Bacteria in Human Feces

Georgina L. Hold, Andreas Schwiertz, Rustam Aminov, Michael Blaut, Harry J. Flint

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Abstract

16S rRNA-targeted oligonucleotide probes were designed for butyrate-producing bacteria from human feces. Three new cluster-specific probes detected bacteria related toRoseburia intestinalis, Faecalibacterium prausnitzii, and Eubacterium hallii at mean populations of 2.3, 3.8, and 0.6%, respectively, in samples from 10 individuals. Additional species-level probes accounted for no more than 1%, with a mean of 7.7%, of the total human fecal microbiota identified as butyrate producers in this study. Bacteria related to E. hallii and the genera Roseburia and Faecalibacterium are therefore among the most abundant known butyrate-producing bacteria in human feces.
Original languageEnglish
JournalApplied and Environmental Microbiology
Volume69
Issue number7
Pages (from-to)4320-4324
ISSN0099-2240
DOIs
Publication statusPublished - 2003
Externally publishedYes

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