Abstract
By measuring enzyme activities in crude extracts and studying the effect of toxic analogs (5-fluoropyrimidines) on cell growth, the metabolism of pyrimidines in Lactococcus lactis was analyzed. Pathways by which uracil, uridine, deoxyuridine, cytidine, and deoxycytidine are metabolized in L. lactis were established. They are similar to those found in Escherichia coli except that lactococci are unable to utilize cytosine.
| Original language | English |
|---|---|
| Journal | Journal of Bacteriology |
| Volume | 176 |
| Issue number | 5 |
| Pages (from-to) | 1514-1516 |
| Number of pages | 3 |
| ISSN | 0021-9193 |
| DOIs | |
| Publication status | Published - 1994 |
Keywords
- Cytidine
- Deoxycytidine
- Deoxyuridine
- Enzymes
- Escherichia coli
- Kinetics
- Lactococcus lactis
- Pyrimidines
- Species Specificity
- Uracil
- Uridine
- 0W860991D6 Deoxycytidine
- 56HH86ZVCT Uracil
- 5CSZ8459RP Cytidine
- W78I7AY22C Deoxyuridine
- WHI7HQ7H85 Uridine
- CYTIDINE
- DEOXYCYTIDINE
- DEOXYURIDINE
- URACIL
- URIDINE
- Eubacteria Bacteria Microorganisms (Bacteria, Eubacteria, Microorganisms) - Gram-Positive Cocci [07700] gram-positive cocci Lactococcus lactis
- CYTIDINE 65-46-3
- DEOXYCYTIDINE 951-77-9
- DEOXYURIDINE 951-78-0
- PYRIMIDINES 289-95-2D
- URACIL 66-22-8
- URIDINE 58-96-8
- 10062, Biochemistry studies - Nucleic acids, purines and pyrimidines
- 10506, Biophysics - Molecular properties and macromolecules
- 13014, Metabolism - Nucleic acids, purines and pyrimidines
- 31000, Physiology and biochemistry of bacteria
- Metabolism
- Physiology
- LACTOCOCCUS lactis