Novel flow quantification of the carotid bulb and the common carotid artery with vector flow ultrasound.

Mads Møller Pedersen, Michael Johannes Pihl, Per Haugaard, Kristoffer Lindskov Hansen, Theis Lange, Lars Lonn, Michael Bachmann Nielsen, Jørgen Arendt Jensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Abnormal blood flow is usually assessed using spectral Doppler estimation of the peak systolic velocity. The technique, however, only estimates the axial velocity component, and therefore the complexity of blood flow remains hidden in conventional ultrasound examinations. With the vector ultrasound technique transverse oscillation the blood velocities of both the axial and the transverse directions are obtained and the complexity of blood flow can be visualized. The aim of the study was to determine the technical performance and interpretation of vector concentration as a tool for estimation of flow complexity. A secondary aim was to establish accuracy parameters to detect flow changes/patterns in the common carotid artery (CCA) and the carotid bulb (CB). The right carotid bifurcation including the CCA and CB of eight healthy volunteers were scanned in a longitudinal plane with vector flow ultrasound (US) using a commercial vector flow ultrasound scanner (ProFocus, BK Medical, Denmark) with a linear 5 MHz transducer transverse oscillation vector flow software. CCA and CB areas were marked in one cardiac cycle from each volunteer. The complex flow was assessed by medical expert evaluation and by vector concentration calculation. A vortex with complex flow was found in all carotid bulbs, whereas the CCA had mainly laminar flow. The medical experts evaluated the flow to be mainly laminar in the CCA (0.82 +/- 0.14) and mainly complex (0.23 +/- 0.22) in the CB. Likewise, the estimated vector concentrations in CCA (0.96 +/- 0.16) indicated mainly laminar flow and in CB (0.83 +/- 0.07) indicated mainly turbulence. Both methods were thus able to clearly distinguish the flow patterns of CCA and CB in systole. Vector concentration from angle-independent vector velocity estimates is a quantitative index, which is simple to calculate and can differentiate between laminar and complex flow. (C) 2014 World Federation for Ultrasound in Medicine & Biology.
Original languageEnglish
JournalUltrasound in Medicine & Biology
Volume40
Issue number11
Pages (from-to)2700-2706
ISSN0301-5629
DOIs
Publication statusPublished - 2014

Keywords

  • blood flow complexity
  • carotid bifurcation
  • Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] human common adult, middle age female, male
  • 06504, Radiation biology - Radiation and isotope techniques
  • 14504, Cardiovascular system - Physiology and biochemistry
  • 14506, Cardiovascular system - Heart pathology
  • Human Medicine, Medical Sciences
  • Medical Sciences
  • carotid bulb circulatory system
  • common carotid artery circulatory system
  • 5MHz transducer transverse oscillation vector flow software computer software
  • vector flow ultrasound clinical techniques, diagnostic techniques
  • Cardiovascular Medicine
  • Radiology
  • ACOUSTICS
  • RADIOLOGY,
  • VELOCITY ESTIMATION
  • MITRAL REGURGITATION
  • WALL SHEAR
  • ATHEROSCLEROSIS
  • ASSOCIATION
  • BIFURCATION
  • VARIABILITY
  • ESTIMATOR
  • ATHEROMA
  • Ultrasound
  • Vector flow
  • Transverse oscillation
  • Carotid artery
  • CAROTID artery
  • Physiology

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