Novel culturing platform for brain slices and neuronal cells

Winnie Edith Svendsen; Fatima Al-Zahraa Al Atraktchi; Tanya Bakmand; Helle Waagepetersen; Maria Dimaki

doi:10.1109/EMBC.2015.7318370

Novel culturing platform for brain slices and neuronal cells

Winnie Edith Svendsen, Fatima Al-Zahraa Al Atraktchi, Tanya Bakmand, Helle Waagepetersen, Maria Dimaki

University of Copenhagen

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

In this paper we demonstrate a novel culturing system for brain slices and neuronal cells, which can control the concentration of nutrients and the waste removal from the culture by adjusting the fluid flow within the device. The entire system can be placed in an incubator. The system has been tested successfully with brain slices and PC12 cells. The culture substrate can be modified using metal electrodes and/or nanostructures for conducting electrical measurements while culturing and for better mimicking the in vivo conditions.

Original language	English
Title of host publication	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Number of pages	4
Publisher	IEEE
Publication date	2015
Pages	346-349
DOIs	https://doi.org/10.1109/EMBC.2015.7318370
Publication status	Published - 2015
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Milan, Italy Duration: 25 Aug 2015 → 29 Aug 2015 Conference number: 37

Conference

Conference	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Number	37
Country/Territory	Italy
City	Milan
Period	25/08/2015 → 29/08/2015

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title = "Novel culturing platform for brain slices and neuronal cells",

abstract = "In this paper we demonstrate a novel culturing system for brain slices and neuronal cells, which can control the concentration of nutrients and the waste removal from the culture by adjusting the fluid flow within the device. The entire system can be placed in an incubator. The system has been tested successfully with brain slices and PC12 cells. The culture substrate can be modified using metal electrodes and/or nanostructures for conducting electrical measurements while culturing and for better mimicking the in vivo conditions.",

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Svendsen, WE, Al Atraktchi, FA-Z, Bakmand, T, Waagepetersen, H & Dimaki, M 2015, Novel culturing platform for brain slices and neuronal cells. in 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, pp. 346-349, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Milan, Italy, 25/08/2015. https://doi.org/10.1109/EMBC.2015.7318370

Novel culturing platform for brain slices and neuronal cells. / Svendsen, Winnie Edith; Al Atraktchi, Fatima Al-Zahraa; Bakmand, Tanya et al.
37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2015. p. 346-349.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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Novel culturing platform for brain slices and neuronal cells

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