Novel block, graft and random copolymers for biomedical applications

Irakli Javakhishvili, Katja Jankova Atanasova, Masaru Tanaka, Søren Hvilsted

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Abstract

Despite the simple structure, poly(2-methoxyethyl acrylate) (PMEA) shows excellent blood compatibility [1]. Both the freezing-bound water (intermediate water: preventing the biocomponents from directly contacting the polymer surface) and non-freezing water on the polymer surface play important roles for this [2]. An artificial lung (oxygenator), already in use, is coated with high MW PMEA prepared by radical polymerization with AIBN [2]. To broaden the possibilities for designing biomedical devices [3] and inspired from these findings we first prepared homo polymers of MEA and their block copolymers with MMA [4] utilizing ATRP. Here we present other block, graft and random copolymers of MEA intended for biomedical applications. These macromolecular architectures have been constructed by employing controlled radical polymerization methods such as RAFT and ATRP.
Original languageEnglish
Publication date2011
Publication statusPublished - 2011
EventNordic Polymer Days 2011 - Stockholm, Sweden
Duration: 15 Jun 201117 Jun 2011
http://www.kth.se/en/che/konferens/npd2011/nordic-polymer-days-june-15-17-2011-1.72785

Conference

ConferenceNordic Polymer Days 2011
Country/TerritorySweden
CityStockholm
Period15/06/201117/06/2011
Internet address

Bibliographical note

Oral presentation.

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