Non-invasive Intravascular Pressure Gradient Estimation using Synthetic Aperture Ultrasound

Lars Emil Haslund, Shamal Surain Kurukuladithya , Malmindi Ariyasinghe, Matthias Bo Stuart, Marie Sand Traberg, Jørgen Arendt Jensen

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This study presents a new method for noninvasive pressure gradient estimations. It combines a new method for estimating the spatio-temporal acceleration of the flowing blood with the Navier-Stokes equation. The method is based on a double cross-correlation approach, which is hypothesized to generate more precise pressure gradients than previous methods. The acceleration is determined by cross-correlating the correlation functions attained from the velocity estimation. Data are acquired using a 5.2 MHz linear transducer in combination with a Verasonics research scanner. A permuted, pulse inverted, interleaved sequence with four virtual sources evenly distributed on the aperture is used. The performance of the method is tested on experimental data, measured on a bifurcation phantom of the common carotid artery. The pressure drop across nine flow cycles varied from -20 Pa to 40 Pa, with a standard deviation of 15.7%.
Original languageEnglish
Title of host publicationProceedings of 2021 IEEE International Ultrasonics Symposium
Number of pages4
Publication date2021
ISBN (Electronic)978-1-6654-0355-9
Publication statusPublished - 2021
Event2021 IEEE International Ultrasonics Symposium - Virtual Symposium, Xi'an, China
Duration: 11 Sept 202116 Sept 2021


Conference2021 IEEE International Ultrasonics Symposium
LocationVirtual Symposium
Internet address


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