Non-invasive Estimation of Pressure Gradients in Pulsatile Flow using Ultrasound

Jacob Bjerring Olesen, Carlos Armando Villagómez Hoyos, Marie Sand Traberg, Jørgen Arendt Jensen

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Abstract

This paper investigates how pressure gradients in a pulsatile flow environment can be measured non-invasively using ultrasound. The presented set-up is based on vector velocity fields measured on a blood mimicking fluid moving at a peak flow rate of 1 ml/s through a constricted vessel. Fields of pressure gradients are calculated using the Navier-Stokes equations. Flow data are acquired to a depth of 3 cm using directional synthetic aperture flow imaging on a linear array transducer producing 1500 image frames of velocity estimates per second. Scans of a carotid bifurcation phantom with a 70% constriction are performed using an experimental scanner. The performance of the presented estimator is evaluated by comparing its results to a numerical simulation model, which geometry is reconstructed from MRI data. The study showed pressure gradients varying from 0 kPa/m to 4.5 kPa/m with a maximum bias and standard deviation of 10% and 13%, respectively, relative to peak estimated gradient. The paper concludes that maps of pressure gradients can be measured non-invasively using ultrasound with a precision of more than 85%
Original languageEnglish
Title of host publicationProceedings of IEEE International Ultrasonics Symposium
PublisherIEEE
Publication date2014
Pages2257-2260
Publication statusPublished - 2014
Event2014 IEEE International Ultrasonics Symposium - Hilton Hotel, Chicago, IL, United States
Duration: 3 Sep 20146 Sep 2014

Conference

Conference2014 IEEE International Ultrasonics Symposium
LocationHilton Hotel
CountryUnited States
CityChicago, IL
Period03/09/201406/09/2014

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