NMR spectroscopic in vitro assay using hyperpolarization

Peter Knox; Neil Cook; Klaes Golman; Haukur Johannesson; Oksar Axelsson; Jan Henrik Ardenkjær-Larsen

NMR spectroscopic in vitro assay using hyperpolarization

Peter Knox, Neil Cook, Klaes Golman, Haukur Johannesson, Oksar Axelsson, Jan Henrik Ardenkjær-Larsen

GE Healthcare

Research output: Contribution to journal › Journal article › Research

Abstract

An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus.
Keyword: hyperpolarization comprising nuclear magnetic resonance spectroscopic in vitro assay laboratory techniques, spectrum analysis techniques,Biochemistry and Molecular Biophysics,10060, Biochemistry studies - General,Methods and Techniques

Original language	English
Journal	U.S. Patent and Trademark Office. Electronic Official Gazette. Patents
ISSN	1554-9550
Publication status	Published - 2009
Externally published	Yes

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title = "NMR spectroscopic in vitro assay using hyperpolarization",

abstract = "An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus. Keyword: hyperpolarization comprising nuclear magnetic resonance spectroscopic in vitro assay laboratory techniques, spectrum analysis techniques,Biochemistry and Molecular Biophysics,10060, Biochemistry studies - General,Methods and Techniques",

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T1 - NMR spectroscopic in vitro assay using hyperpolarization

AU - Knox, Peter

AU - Cook, Neil

AU - Golman, Klaes

AU - Johannesson, Haukur

AU - Axelsson, Oksar

AU - Ardenkjær-Larsen, Jan Henrik

PY - 2009

Y1 - 2009

N2 - An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus. Keyword: hyperpolarization comprising nuclear magnetic resonance spectroscopic in vitro assay laboratory techniques, spectrum analysis techniques,Biochemistry and Molecular Biophysics,10060, Biochemistry studies - General,Methods and Techniques

AB - An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus. Keyword: hyperpolarization comprising nuclear magnetic resonance spectroscopic in vitro assay laboratory techniques, spectrum analysis techniques,Biochemistry and Molecular Biophysics,10060, Biochemistry studies - General,Methods and Techniques

M3 - Journal article

SN - 1554-9550

JO - U.S. Patent and Trademark Office. Electronic Official Gazette. Patents

JF - U.S. Patent and Trademark Office. Electronic Official Gazette. Patents

ER -

NMR spectroscopic in vitro assay using hyperpolarization

Abstract

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