NMR spectroscopic in vitro assay using hyperpolarization

Peter Knox, Neil Cook, Klaes Golman, Haukur Johannesson, Oksar Axelsson, Jan Henrik Ardenkjær-Larsen

Research output: Contribution to journalJournal articleResearch


An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus.
Keyword: hyperpolarization comprising nuclear magnetic resonance spectroscopic in vitro assay laboratory techniques, spectrum analysis techniques,Biochemistry and Molecular Biophysics,10060, Biochemistry studies - General,Methods and Techniques
Original languageEnglish
JournalU.S. Patent and Trademark Office. Electronic Official Gazette. Patents
Publication statusPublished - 2009
Externally publishedYes


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